James Kirk - Yvonne Strahovski (Chuck)

Spock - Jordana Brewster (Fast & Furious, D.E.B.S.)

Nyota Uhura - Leonard Roberts (Buffy the Vampire Slayer, Heroes)

Leonard McCoy - Lena Headey (Sarah Connor Chronicles)

Hikaru Sulu - Grace Park (Battlestar Galactica)

Montgomery Scott - Catherine Tate (Doctor Who)

Pavel Chekov - Olesya Rulin (High School Musical)

And bonus cast...

Christopher Pike - Torri Higginson (Stargate Atlantis)

Gaila - Tom Welling (Smallville)