After the invasion, billions of dollars were removed from the Panamanian banking system by federal mandate, just in time to help bail out the failed S & L industry which collapsed under the weight of corruption and "deregulation."
This involved him in Bush's Iran-Contra program, a triangular trade which involved selling arms to Iran (for a private profit), importing cocaine into the US (for a private profit) and delivering arms to the Contras (for a private profit.)
Deemed a "narco-terrorist," Noriega was the main banker for the cocaine trade.
The "surgical strike" designed to remove CIA partner Manual Noriega from office, killed an estimated 10,000 civilians.
The Road to Iraq and Afghanistan (and maybe Iran and Pakistan) started with the invasion of Panama under the direction of George H.W. Bush, the father.