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α-Casein Exorphins


Definition

a-Casein exorphins are peptides isolated from a-Casein1. They have morphine-like opioid (narcotic) activity and hence are termed exorphins1.

Discovery

a-Casein exorphins were first purified from pepsin treated hydrolysates of a-Casein1. Their opiod activity was then determined by biochemical assays1.

Classification

a-Casein exorphins belong to the class of opioid peptides that also includes exorphins that are proteins absorbed by the digested food and endorphins that are produced by the body itself1.