a-Casein exorphins are peptides isolated from a-Casein1. They have morphine-like opioid (narcotic) activity and hence are termed exorphins1.
Discovery
a-Casein exorphins were first purified from pepsin treated hydrolysates of a-Casein1. Their opiod activity was then determined by biochemical assays1.
Classification
a-Casein exorphins belong to the class of opioid peptides that also includes exorphins that are proteins absorbed by the digested food and endorphins that are produced by the body itself1.