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| Long-lived mutant yeast. Biologists have created baker's yeast capable of living to 800 in yeast years without apparent side effects. (Credit: Image courtesy of University of Southern California) |
The basic but important discovery, achieved through a combination of dietary and genetic changes, brings science closer to controlling the survival and health of the unit of all living systems: the cell.
"We're setting the foundation for reprogramming healthy life," said study leader Valter Longo of the University of Southern California.
"We got a 10-fold life span extension that is, I think, the longest one that has ever been achieved in any organism," Longo said. In 2005, the same research group reported a five-fold life span extension in the journal Cell. Normal yeast organisms live about a week.