Amphibians are among the groups hardest hit by today's many strikes against wildlife. As many as half of all species are under threat. Hundreds are sliding toward extinction, and dozens are already lost. The declines are rapid and widespread, and their causes complex—even at the ravine near Limón the bulldozer is just one hazard of many. But there are glimmers of hope. Rescue efforts now under way will shelter some animals until the storm of extinction passes. And, at least in the lab, scientists have treated frogs for a fungal disease that is devastating populations around the world.