1928 - Aschheim-Zondek: Also known as the A-Z Test, this very first scientific pregnancy test was developed in Germany. It involved several subcutaneous injections of varying amounts of a woman's urine into the backs of immature female mice weighing between five and eight grams. One hundred hours after the first injection, the mice were killed and the ovaries were examined. The A-Z test is named for German researchers Selmar Aschheim (1878-1965) and Bernhard Zondek (1891-1966). Zondek was the first person to describe the ovarian hormone and earned worldwide renown for discovering gonadotropins. He and Aschheim both worked at Charité Hospital's Women's Clinic in Berlin (now the Institute of Experimental Endocrinology, CCM).