Casein kinases are Ser/Thr protein kinases that have been implicated in cell cycle control, circadian rhythm, DNA repair and other cellular processes1. Several substrates of casein kianses have been identified and even synthesized artificially2.
Discovery
Casein kinase activity associated with the endoplasmic reticulum of mammary glands was first characterized in 19743.
Classification
Casein kinase belongs to the kinase family of proteins and its substrates that are proteins involved in various cellular processes are numerous in number. Two casein kinases have been widely studied: Casein kinase I and II3.