The Trusted Computing Group (TCG) is an alliance of Microsoft, Intel, IBM, HP and AMD which promotes a standard for a `more secure' PC. Their definition of `security' is controversial; machines built according to their specification will be more trustworthy from the point of view of software vendors and the content industry, but will be less trustworthy from the point of view of their owners. In effect, the TCG specification will transfer the ultimate control of your PC from you to whoever wrote the software it happens to be running. (Yes, even more so than at present.)
TC provides a computing platform on which you can't tamper with the application software, and where these applications can communicate securely with their authors and with each other. The original motivation was digital rights management (DRM): Disney will be able to sell you DVDs that will decrypt and run on a TC platform, but which you won't be able to copy. The music industry will be able to sell you music downloads that you won't be able to swap. They will be able to sell you CDs that you'll only be able to play three times, or only on your birthday. All sorts of new marketing possibilities will open up.