A thumb’s up for “I’m good.” The rubbing of a pointed forefinger at another for “shame on you.” The infamous and ubiquitous middle finger salute for—well, you know. Such gestures that convey meaning without speech are used and recognized by nearly everyone in our society, but to someone from a foreign country, they may be incomprehensible.

The opposite is true as well. Plop an American in a foreign land and he or she may be clueless to the common gestures of that particular culture. This raises a provocative question—does culture influence the brain"

The answer is yes, reports Istvan Molnar-Szakacs, a researcher in the UCLA Tennenbaum Center for the Biology of Creativity, and Marco Iacoboni, director of the Transcranial Magnetic Stimulation Lab at the Ahmanson-Lovelace Brain Mapping Center of UCLA's Semel Institute for Neuroscience and Human Behavior. Their research appears in the current issue of the journal PLoS ONE and is available online at http://www.plosone.org/doi/pone.0000626.