clipped from: www.abc.net.au   
Rob Taylor

An Australian teenage girl has become the world's first known transplant patient to change blood groups and take on the immune system of her organ donor, say doctors.

Demi-Lee Brennan with Dr Stephen Alexander and Dr Stuart Dorney

Demi-Lee Brennan with Dr Stephen Alexander (left) and Dr Stuart Dorney (right) at Westmead Hospital in Sydney - the teenager no longer needs anti-rejection drugs

A Sydney-based team describe the case in the latest issue of The New England Journal of Medicine.


Now 15, Demi-Lee Brennan received a donor liver when she was 9 years old and her own liver failed.


Her body changed blood group from O negative to O positive when she became ill while on drugs to avoid rejection of the organ by her body's immune system.


stem cells from the donated liver then invaded Brennan's body's bone marrow and triggered her entire immune system to switch to that of the donor's

meaning the teen no longer needed anti-rejection drugs

Doctors say they have no explanation for Brennan's recovery, and describe her as a "one-in-six-billion miracle"